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Enabling the mobility of people and goods means connecting people and nations and fostering economic and cultural exchanges and social development. As the population and the economy grow, transport demand continues to increase; as a consequence the transport sector currently accounts for one third of the total consumption of energy vectors, the oil products being more than 90%. The complexity of the sector requires deploying a diverse mix of decarbonization solutions to meet the challenges within each of its four main segments: roadways, railways, aviation, and navigation. This scenario urges brave but realistic regulatory frameworks and technologies suitable to create a fertile environment for innovation considering the actions and the strategies also as a function of the geographies, unleashing the potential of research while fostering virtuous behaviours of citizens in all transport modes.