Mindful Parenting is one of the most recent applications of mindfulness, with the aim of promoting well-being in the parent-child relationship and increasing parenting skills. Mindfulness interventions are known to enhance attention and self-regulation skills in parents’ practitioners, helping them to pay attention, in a non-judgmental way, to the present moment and to the interaction with their child. The purpose of this study is to test the effects of a Mindful Parenting program in a sample of 16 mothers of children with behavioural disorders. Our findings suggest significant positive changes in no-reaction mindfulness skill and a significant decrease in negative parenting practices. These results are encouraging and show that mindfulness-based approach may represent a valuable help for mothers of children with behavioural disorders.